CRISPRclean Metatranscriptomics rRNA Depletion kits

Be sure not to miss vital, low-abundance RNA signals when studying the function and activity of metatranscriptomes with CRISPRclean Metatranscriptomics rRNA depletion kits.

CRISPRclean Metatranscriptomics rRNA Depletion kit

Designed for Illumina NGS libraries the CRISPRclean Metatranscriptomics rRNA Depletion kit is a combination of the Human and Pan Bacterial rRNA depletion kits, ideal for human microbiome studies enabling improved sensitivity and performance.


  • Designed to target human and over 200 bacterial species in a single depletion workflow
  • Access low total RNA inputs below 1 ng previously not possible with pre-library depletion methods. Tested down to 100 pg of Total RNA (10 cells)
  • Save time and streamline your workflow by pooling multiple samples in a single depletion reaction post-library preparation.
Species Human, over 200 bacteria
Designed to deplete Human: 5S, 5.8S, 18S, 28S, 45S (precursor), mito 12S, and 16S rRNA; Bacteria: 5S, 16S, and 23S rRNA
Recommended library prep NEB Next Ultra II Directional RNA Library Prep for Illumina

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