CRISPRclean is a proprietary technology that utilizes the CRISPR/CAS system to deplete unwanted nucleic acid molecules from sequencing libraries. The process fits seamlessly within standard NGS workflows and works with most commercially available library preparation solutions. Applications of the technology include host organism depletion, ribosomal RNA depletion, repetitive sequence depletion, allele specific depletion or depletion of contaminating organisms in accessible sample types such as saliva.
Features and benefits:
- Lower sample inputs and increased sensitivity
- Increased throughput with simplified workflows
- Reduced sequencing costs
- Removal of reference bias