Improved Single Cell Transcriptional Profiling with CRISPRclean

Increase your ability to detect rare transcripts and to confidently analyze differential gene expression data using CRISPRclean on 10x Genomics single cell RNA sequencing libraries.

CRISPR Powered Universal Infectious Disease Assay

Detect 4-10x fold more species and reads aligned from metagenomic samples from the source of any co-infection and the host transcriptional response in a single workflow with Jumpcode CRISPRclean technology.

Cut out the ribosomal noise and focus your RNA sequencing efforts

Improve sensitivity and increase ability to detect rare transcriptomic events with CRISPRclean ribosomal RNA depletion products.

Keith Brown explains how CRISPRclean improves transcriptional profiling and increases read coverage of 1000s of transcripts by removing the uninformative targets from single cell libraries while preserving cell type identification.

Jumpcode Genomics Secures $21M in Series B Funding

Investors include Baird Capital, Arboretum Ventures and LYZZ Capital; funding will accelerate commercialization of CRISPRclean™ next-generation sequencing technology Life sciences industry veteran Frank Witney joins […]

Q&A: A jump to the next step in sequencing

Kelsey Kaustinen details how Jumpcode’s CRISPRclean technology unites NGS and CRISPR/Cas editing in a Q&A with our Chief Scientist in the current issue of Drug […]

Jumpcode Genomics Exits Stealth Mode, Unveils Technology that Addresses the ‘Needle in the Haystack’ Problem of Molecular Biology

Patented CRISPRclean™ Technology is a Foundational Tool that Improves the Performance of Next-Generation Sequencing and Other Molecular Workflows by Increasing Sensitivity, Reducing Costs and Enabling Novel […]


Using JUMPCODE’s accurate, efficient depletion techniques together with high-throughput sequencing has been a real turning point for my research. We can now generate data from enough low amount of samples to have real statistical significance.

Laura Steinke img

Laurey Steinke, PhD
Associate Professor, Nebraska Medical Center

CRISPRclean Technology


CRISPRclean is a proprietary technology that utilizes the CRISPR/CAS system to cut through the noise by removing unwanted nucleic acid molecules from sequencing libraries while preserving the representational integrity of the non-targeted sequences.

Researchers can benefit from an increased sensitivity and specificity in their areas of interest, use scarce and precious samples, and focus their sequencing cost on regions they care about without the worry of bias.

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Researchers are using CRISPRclean kits in their RNA sequencing workflows to gain deeper insights in gene expression and transcriptome profiling studies. Learn more about CRISPRclean ribosomal RNA depletion products


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About us

Founded in 2016, Jumpcode Genomics aims to improve the understanding of human biology and the contribution to disease. The company's proprietary CRISPRclean technology utilizes the CRISPR/Cas system to deplete unwanted nuclei acid molecules from sequencing libraries.

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