CRISPRClean Bulk Ribodepletion Reagents (Human, Mouse, Rat, Pan Bacteria)

Multiplex rRNA depletion with our bulk reagents


CRISPRClean Bulk Ribodepletion Reagents remove overabundant human, mouse rat and bactieral rRNA from RNA-Seq libraries to improve sequencing sensitivity and performance. This protocol was designed for high-throughput screening applications by moving the depletion step post-library prep and enabling depletion on multiplexed pools of up to 256 multiplexed samples.


Discover more from mixed microbial samples

Complex samples may have a mixture of bacterial and human cells, all actively expressing ribosomal RNA. Take advantage of the power of CRISPRclean for effective ribosomal RNA removal. CRISPRclean can also remove uninformative bacterial reads in-vitro ahead of sequencing – redistributing >80% of sequencing reads to enable identification of lower expressing, biologically relevant transcripts.



  • Use for high-throughput transcriptome profiling screening applications
  • Deplete up to 16  RNA-Seq libraries in a single pool
  • Deplete up to 80% of eukaryotic and bacterial rRNA
  • Automation-friendly protocol

Catalog KIT1030
Samples per kit 256, 16 reactions
Sample types Finalized libraries with mixtures of eukaryotes and prokaryotes
Multiplex 16 samples per rection
Compatible species Human, mouse, rat, 212 bacteria
Designed to deplete Human 5S, 5.8S, 18S and 28S, 45S rRNA precursor, mitochondrial 12S and 16S rRNA genes. 212 bacteria representing all phyla: 5S, 16S, and 23S rRNA gene.

CRISPRClean Bulk Ribodepletion Reagents (Human, Mouse, Rat, Pan Bacteria)

$7,680 Add to Cart


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